用于葡萄糖检测的荧光纳米生物传感器-中国科技论文在线.PDF

中国科技论文在线 用于葡萄糖检测的荧光纳米生物传感器 冷凤，莫志宏，王天丽** 401331 5 摘要： 关键词： 10 中图分类号：O65 Fluorescent nanobiosensor for glucose detection LENG Feng, MO Zhihong, WANG Tianli (College of Chemistry and Chemical Engineering, Chongqing University, Chongqing 401331) 15 Abstract: With the increase of the incidence of diabetes, glucose detection has received more and more attention. In this paper, the related contents of fluorescence nano-biosensors for glucose detection are reviewed, including the principle of fluorescence nanometer biosensors for glucose detection, fluorescence nanometer biosensors for glucose sensing six typical emission/interaction nanomaterials and characteristics, and fluorescence nano biosensors. Application in the detection of glucose. Finally, 20 the prospects for the application of fluorescence nanometer biosensors to detect glucose are discussed. Key words: glucose; biosensor;fluorescence;nanomaterials 0 引言 25 糖尿病由于胰岛素分泌缺陷或其生物作用受损，患者以高血糖为特征的一种代谢性疾 病。糖尿病患者会因血糖浓度控制不足而导致一系列并发症，如心脏病、中风、肾和神经损 伤、截肢和失明等，这些都是由于血糖水平长时间不受控制造成的。随着社会的高度发展， 物质生活的极大丰富，糖尿病的发病率越来越高，并且呈现年轻化的趋势。加之葡萄糖检测 作为预防、诊断、治疗糖尿病的第一步，因此葡萄糖检测技术受到高度关注。特别是能够快 30 速、准确、灵敏、无创的血糖监测手段，能为糖尿病患者提供新的血糖监测选择，具有重大 意义。 目前葡萄糖检测方法有HPLC 法、分光光度法、旋光度法、气相色谱法、传感器法等， 在近十年里，传感器的研究最多。荧光纳米葡萄糖生物传感器是传感器