多发性骨髓瘤诊断和治疗.pptVIP

* 反应停及反应停联合方案治疗R/RMM Study Regimen No. of Pts ORR CR (No. of Pts) Singhal, 1999 Thalidomide 200-800 mg/day 84 32% 2 Barlogie, 2001 Thalidomide 200-800 mg/day 169 37% 3 Kumar, 2003 Thalidomide 200-800 mg/day 32 31% 0 Richardson, 2004 Thalidomide 200-600 mg/day 30 43% 0 Dimopoulos, 2001 Thalidomide 200-400 mg + Dexamethasone 20 mg 44 55% 0 Palumbo, 2001 Thalidomide 100 mg + Dexamethasone 40 mg 77 66% 2 Dimopoulos, 2004 Thalidomide/Dexamethasone/ Cyclophosphamide 53 60% 3 Garcia-Sanz, 2004 Thalidomide/Dexamethasone/ Cyclophosphamide 49 68% 5 沙利度胺一线治疗MM MDACC MAYO