第四和五章：食品过敏及过敏原信息.ppt

蛋黄中的主要过敏原 Protein 蛋白质 Name 分类名 molecular weight 分子量(kDa) Content in egg white 鸡蛋白中的含量(%) Ovomucoid (*key) 卵类粘蛋白 Gal d 1 28000 11 Ovalbumin 卵清蛋白 Gal d 2 45000 54 Ovotransferrin or conalbumin 卵铁传递蛋白或伴清蛋白 Gal d 3 78000 12 Lysozyme 溶菌酶 Gal d 4 14000 3.4 cross-reactions交叉反应: allergy to egg can be correlated to allergy to bird feathers 鸡蛋敏感症与鸟类羽毛敏感症之间有相关性 the major cross-reacting determinants are the livetins from egg yolk. 主要交叉反应的决定因素是蛋黄中的卵黄蛋白 Allergens of Plant Origin三、来源于植物的过敏原 The vegetable foods that most commonly cause hypersensitivity symptoms致敏性蔬菜种类 hazelnut 榛实 Walnut 胡桃 Brazil nut 巴西坚果 Apple 苹果 Almond 杏仁 Peach 桃子 Plum 李子 Cherry 樱桃 Peanut 花生 Peas 豌豆 Carrot 胡萝卜 parsley 欧芹 Celery 芹菜 Orange 橘子 Strawberry 草莓 Cereals 谷物 The ranking lists vary depending on各种蔬菜致敏程度的影响因素 1）the age of the patients 病人的年龄 2）the methods of diagnosis 诊断方法以及 3）the geographic location of the population 地理环境 Fruits, Nuts, and Vegetables （一）水果、坚果和蔬菜 More than 90% of patients with sensitization to vegetable foods had concomitant sensitization to pollen 90% 以上的蔬菜敏感症总是伴随着花粉敏感症而来 In a group of birch pollen allergies the patients with additional hypersensitivity to nuts and apples had： 在一组同时有另外的坚果和苹果超敏性的桦树花粉敏感症病人中 (1) more severe symptoms during the pollen season 在花粉季节症状严重加重 (2) higher values of IgE to birch and hazel pollen, 桦树和榛子花粉的IgE值较高 (3) a larger area of the skin prick test reactive to birch and hazel pollen compared to the group without apple and nut allergy 与那些没有坚果和苹果超敏性病人相比，桦树和榛子花粉的皮肤穿刺试验反应区域要大得多。 The symptoms 主要症状： Mainly from the mouth and pharynx, with itching, swelling of the lips, tongue, and throat. syndrome. 从嘴到咽发痒，嘴唇、舌头以及咽喉肿胀 These symptoms are called the “oral allergy” “口腔敏感综合症” cross-reactions交叉反应: 1）A sensitization to mugwort pollens and different spices, the so-called mugwort-celery-spices syndrome, has been reported 艾蒿及其不同种艾属植物的花粉有致敏性，又称艾蒿-芹菜--香料综合症。 2） It was shown by prick, RAST studies, and RAST inh