小儿胸膜肺母细胞瘤_曾骐.pdfVIP

200 1 12 17 6 　Chin J T horac Cardiovasc Surg, December 200 1, Vol .17 No .6 ·343 · ·· 小儿胸膜肺母细胞瘤 曾骐　周春菊　贺延儒　尹慧英 　　【】　　(PPB)、。 　 22 , Dehuer II 15 、III 7 , 。 　22 3 ～ 10 , 1 ∶1。 , 19 , 13 。 X : 4 , 1 , 、11 , 4 , 2 。 (、) 100%, 77.3%, (5.4 ±6.2 )。 0.5 ～ 24 。 18 , 。 1 ～ 12 。 9 , 2 27.3%, 5 9.1%。 13 , 1 d ～26 。 　、 (PB), 。 、。 【】　　　　　 Pleuropulmonary blastoma in children ZENGQi, ZHOUChunj u, HE Yanru, et al.Bejiing Children Hospital, Cap ital University of Medical ciences, Beij ing 100045, China. 【Ab stract】Objective:To discuss the diagnosis, t reatment and prognosis o pleuropulmonary blastoma in children.Methods: The data o 22 chi ldren with pleuropulmonary blastoma was reviewed.Results:The age was 3 months to 10 y ears.The male emale ratio was 1 ∶1.18 chi ldren were treated surgi cally.The durat ion o ollow-up was 1to 144 months.The earliest symptom was cough in 22 patients, 19 children had ever, and dyspnea in 13.Chest radiogram showed cy st ormation in 4 children, pneumothoax in 1, patchy shadows in 11, pleural e usion in 4 and mediastinal mass in 2.The duration rom initial to de initive diagnosis was 0.5 to 24 months.The duration rom onset o symptom to de initive diagnosis was 1 to 26 months.18 children were underwent operations, and chemotherapy only .9 chi ldren have been survived.2-year and 5-y ear survival rate were 27.3%and 9.1%respectively.The duration rom diagnosi s to death was 1 day to 26 months.Conclusion:Pleuropulmonary blastoma in children is a rare malignant neoplasm, whi ch is quit e di erent rom adult i n histology, genetic, clinical evidence and prognosis.Misdiagnosis is requent .Early diagnosis and proper treatment is the key or getting a good outcome. 【Key words】　Pleural neoplasms　　Pulmonary blastoma 　　Child 　　(pleuropulmonary blastoma, PPB ) 2 5 cm。14 、8 。 〔1〕