课件：感染病患者多重耐药菌感染风险诊断.pptVIP

* The introduction of every new class of antimicrobial agents is followed by emergence of resistance. By 1962, penicillin-resistant S. aureus were a major threat in hospitals and nurseries. By the 1970s, methicillin-resistant S. aureus had emerged and spread, a phenomenon that encouraged widespread use of vancomycin. In the 1990s, vancomycin-resistant enterococci emerged and rapidly spread; most of these organisms are resistant to other traditional first-line antimicrobial drugs. In 1997, the first S. aureus strains with reduced susceptibility to vancomycin were documented, prompting con