OIE《水生动物疫病诊断手册》鲍鱼疱疹病毒感染2018版2.4.1章只用条款4.3.1.2.3..pdfVIP

C H A P T E R 2 . 2 . 1 . I N F E C T I O N W I T H A B A L O N E H E R P E S V I R U S 1. Scope1 For the purpose of this chapter, abalone viral ganglioneuritis (AVG) is considered to be infection with abalone herpesvirus (AbHV). 2. Disease information 2.1. Agent factors Abalone herpesvirus (AbHV) is the aetiological agent of abalone viral ganglioneuritis (AVG), a contagious disease of abalone species in Australia (Ellard et al., 2009; Hooper et al., 2007) and possibly of species in other countries (Chang et al., 2005; Wang et al., 2004). Comparison of nucleotide sequences of AbHV VIC and Ostreid Herpesvirus-1 (Davison et al., 2009; Le Deuff Renault, 1999) over common coding regions identified similarities ranging from 19% to 53%, indicating that these viruses share a low level of sequence similarity (Savin et al., 2010), and it has been assigned tentatively as a second member of the Malacoherpesviridae. Purified AbHV particles (Tan et al., 2008) observed by transmission electron microscopy are enveloped and icosahedral with electron dense cores and 100‒110 nm in diameter. The intranuclear location of AbHV particles, their size and ultrastructure are characteristic of members of the Herpesviridae. Isopycnic gradient centrifugation (in potassium tartrate and caesium chloride density gradients) indicated a virus particle buoyant density of 1.17‒ ‒1 (Tan et al., 2008). 1.18 g ml 2.1.1. Aetiological agent, agent strains Herpesviruses associated with abalone disease have been reported from Chinese Taipei and Australia. Comparison of nucleotide sequences of AbHV VIC and AbHV Taiwan over t