软组织超声散射子特性研究探究的功率谱方法资料.docVIP

Study on the properties of ultrasonic scatterer in soft tissues with power spectrum method MA Lang GUO Jian-zhong* ZHU Zheng-yu LIU Bo (Institute of Applied Acoustics,Shaanxi Normal University, Shaanxi’Key Laboratory of Ultrasound, xi’an shaanxi 710062，China) [Abstract] Objective The frequency and phase information of ultrasound backscattered RF signal from biological soft tissues is related to the microstructures of tissue. Frequency-dependent information can be obtained from the power spectrum of ultrasound backscattered RF signal. Methods The slope and intercept of the line, which is fitted by power spectrum of ultrasonic backscattered signal from soft tissues, are used to estimate the property parameters of ultrasonic scatterer, such as effective average radius of scatterers, etc. Results This paper has fitted the theoretical power spectrum and measured power spectrum of ultrasonic backscattered signal from experimental phantom, and compared with the fitted values. There are good agreement between the two fitted values. Conclusions The linear fitted values of theoretical power spectra and measured power spectrum of ultrasonic backscattered signal are not good agreement when the scatterer size is too big. [Key words] scatterer size；power spectrum；linear fitting 软组织超声散射子特性研究的功率谱方法 马浪 郭建中[基金项目] 国家自然科学基金项目[基金项目] 国家自然科学基金项目和陕西省自然科学基金项目(SJ08A03)资助 [作者简介] 马浪(1984-)，男，陕西横山人，汉族，硕士研究生，研究方向为医学超声 [*通讯作者] 郭建中，男，副教授，博士；E-mail:guojz@snnu.edu.cn (陕西师范大学应用声学研究所 陕西省超声学重点实验室，陕西 西安，710062) [摘要] 目的 生物软组织超声背散射射频信号的频率和相位信息与组织的微观结构有关，频率信息可以从背散射信号的功率谱中得到。方法 对软组织超声背散射信号的功率谱线性拟合以后，可利用拟合直线的斜率和截距来估计组织超声特征散射子的粒径等特性参数。结果 本文对实验仿体超声背散射信号的理论功率谱和测量功率谱进行了线性拟合和拟合值的比较，二者的拟合值吻合较好。结论 当软组织超声特征散射子的粒径较大时，背散射信号理论功率谱和测量功率谱的线性拟合值不能够较好地吻合。 [关键词] 散射子粒径；功率谱；线性拟合 中图分类号 [O426.9];TN911.72 文献标识码 A 前言 传统的B型超声成像利用软组织超声背散射射频信号的幅度包络信息，丢弃了与组织微观结构有关的频率和相位信息，没有充分地利用回波信号。许多学者致力于利用软组织超声背散射信号的频率和相位信息进行软组织微结构特征的研究，探寻超声诊断技术在生物软组织生理病理诊断中的应用。 当生物软组织发生病变以后，组织的衰减系数、弹性特性以及超声特征散射子的粒径和数浓度(