电针百劳、中渚穴对健康志愿者脑功能性磁共振成像作用的研究.pdfVIP

20 appropriate healthy young volunteers from Guangzhou university received EX-HN15 Ac and EX-HN15+SJ3 Ac randomly,which to neddle all right acupoints,use acusector on basic of acuesthesia,dilatational wave,and withdraw needles after 30 minutes. the resting-state fMRI data were acquired before and 5 min after the withdraw of AC. ALFF of encephalic regions were calculated using REST software and one-sample t-test analys is was performed on the intragroup data acquired after Ac by statistical parametric mapping 5 ( SPM5),to get the maps of ALFF changes induced by EX-HN15 Ac and EX-HN15+SJ3 Ac respectively for analyzing the difference between them finally. Result 1.Compared with the before acupuncture, EA EX-HN15 and EX-HN15+SJ3 points can cause significant changes of ALFF,including cerebral cortex (involved in frontotemporal and parietooccipital) and the limbic system,etc,which show that acupuncture points raised two sets of neural activity in the brain. 2.EA EX-HN15 in healthy volunteers evokes deactivation of ALFF of the right Rectus lobe, orbital frontal gyrus, left posterior cingulate,left precuneus.Deactivation of MPFC(the Rectus lobe,orbital frontal gyrus)and MPC(posterior cingulate, precuneus) suggest the presence of DMN.Activation of the right precentral gyrus,insula,supplementary motor area,the left anterior cingulate gyrus,antero-middle cingulate and Middle cingulate gyrus in terms of regard as anti-correlated network of DMN. 3.EA EX-HN15 and SJ3 in healthy volunteers induce deactivation of ALFF of the right precuneus,supplementary motor area,paracentral lobule,thalamus,rectus frontal,the medial orbital frontal,MPFC(rectus frontal,the medial orbital frontal)and MPC(precune