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腹腔镜手术中央,周围血流动力学变化及应用IPC后的相应变化
CentralandPeripheralAdverseHemodynamicChangesDuringLaparoscopicSurgeryandTheirReversalwithaNovelIntermittentSequentialPneumaticCompressionDevice
SiamackAlishahi,FRCS,*NadirFrancis,FRCS,*SallyCrofts,FRCA,+LesleyDuncan,FRCA,+AmitatiBickel,MD,*andAlfredCuschieri,MD,FRSE*
FromtheDepartmentsof*SurgeryMolecularOncologyand+Anaesthesia,NinewellsHospitalandMedicalSchool,UniversityofDundee,Dundee,Scotland
Objective
Tostudytheinfluenceofanovelintermittentsequentialpneumaticcompressiondevice(Lympha-press)ontheadversecardiacandperipheralhemodynamicchangesinducedbypositive-pressurepneumoperitoneum(PPPn)inlaparoscopicsurgery.
SummaryBackgroundData
CreationofPPPnisknowntocauseadversecentralandperipheralhemodynamicchanges.AnintrasubjectobservationalstudywasundertakentoquantitatetheseadversechangesandtoassesstheinfluenceofanintermittentsequentialpneumaticcompressionsystemontheseadversehemodynamicchangesduringlaparoscopicsurgerywithPPPn.
Methods
Thestudyinvolved16consecutivepatientsundergoinglaparoscopicsurgerywithPPPnof12mmHgand30ohead-uptiltposition.ThefollowingperipheralhemodynamicrecordingsweremadeusingDopplerultrasound:peaksystolicvelocity(PSV),enddiastolicvelocity(EDV),andcross-sectionalareaofthefemoralvein.CentralmonitoringincludedcardiacoutputandstrokevolumebytransesophagealDoppler,bloodpres-sure,andpulse.ThehemodynamicstatebasedontheseparameterswasassessedbeforeinductionofPPPnwiththeanesthetizedpatientinthesupineposition,afterinductionofPPPnandhead-uptiltpositionwithLympha-pressoff,andduringPPPnandhead-uptiltpositionwithLympha-presson,andafter.desufflationwiththepatientinthesupinepositionundergeneralanesthesia.
Results
Positive-pressurepneumoperitoneumandthehead-uptiltpositionresultedina33%reductioninPSV,a21%reductioninEDV,anda29%increaseincross-sectionalareaofthefemoralvein.Thiswasassociatedwitha20%reductionincardiacoutputandan18%reductioninstrokevolume.ActivationofLympha-pressduringPPPnandthehead-uptiltpositionresultedina129%increaseinPSVanda55
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