帕金森病的非运动症状培训课件.pptVIP

0% 10% 20% 30% 40% 50% 60% 70% 80% Placebo (n=23) Pramipexole 0.26mg (n=27) Pramipexole 0.7mg (n=23) Pramipexole 3.5mg (n=15) Fluoxetine 20mg (n=30) 普拉克索对MDD？？的效果 Corrigan MH et al. Depression and Anxiety 2000, 11: 58-65 Responder* *Patients with CGI-SI Score 2 or less Duration of treatment: 8 weeks 双盲，多中心，随机研究(n=174) weeks 0 1 2 3 4 5 6 7 8 9 Placebo Pramipexole 0.26 mg Pramipexole 0.70 mg Pramipexole 3.50 mg Fluoxetine 20 mg 0 -3 -6 -9 -12 -15 自基线平均改变 (HAM-D 评分) * vs placebo: p 0,05 Washout Corrigan MH et al., Depression and Anxiety 2000, 11: 58-65 ** 普拉克索对MDD的效果 Prospective observatio