多重耐药菌感染的治疗.pptVIP

J Antimicrob Chemother. 2008 Jun;61(6): Efficacy and safety of high-dose ampicillin/sulbactam vs. colistin as monotherapy for the treatment of multidrug resistant Acinetobacter baumannii ventilator-associated pneumonia METHODS A prospective cohort study in adult critically ill patients with VAP Amp/Sulb (9 g every 8h) or COL (3 MIU every 8h) intravenously RESULTS A total of 28 patients were enrolled (15 COL, 13 Amp/Sulb). Resolution of symptoms and signs occurred in 60% (9/15) of the COL group and 61.5% (9/13) of the Amp/Sulb group, improvement in 13.3% (2/15) vs. 15.3% (1/13) and fa