呼吸治疗肺保护施丽萍指南.pptVIP

呼吸机治疗的肺保护策略 浙江大学医学院附属儿童医院 施丽萍 呼吸机相关性肺损伤 acute parenchymal lung injury and an acute inflammatory response in the lung. cytokines →alveoli and the systemic circulation →multiple organ dysfunction mortality↑ 呼吸机相关性肺损伤ventilator-induced lung injury 容量性损伤 Volutrauma（large gas volumes ） 压力性损伤 Barotrauma（high airway pressure ） 不张性损伤 Atelectotrauma（alveolar collapse and re-expansion） 生物性损伤 Biotrauma（increased inflammation ） 肺 损 伤 病 理 alveolar structural damage pulmonary edema、 inflammation、 fibrosis surfactant dysfunction other organ dysfunction exacerbate the disturbance of lu