乳腺叶状囊肉瘤的诊断和治疗.docVIP

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DOC格式论文,方便您的复制修改删减 乳腺叶状囊肉瘤的诊断和治疗 (作者:___________单位: ___________邮编: ___________) 作者:许学杰 刘国泉 林力生 林志君 【摘要】 目的:探讨乳腺叶状囊肉瘤的诊治方法。方法:回顾分析经病理证实的18例乳腺叶状囊肉瘤患者临床资料。结果:本病在10岁和40岁高发,以无痛性乳房肿块为主要表现,术前均未明确诊断,行肿瘤扩大切除术13例,改良根治术3例,单纯乳房切除术2例;局部复发率11.1%(2/18),愈后良好。结论:辅助检查对乳腺叶状囊肉瘤定性诊断帮助不大,确诊要靠病理检查;治疗以肿瘤扩大切除术为主,局部复发后再次手术仍能取得较好效果。 【关键词】 乳腺叶状囊肉瘤;诊断;治疗   Abstract Objective:To inquire into methods for the diagnosis and treatment of breast cystosarcoma phyllodes. Methods: Review and analyze clinical materials of 18 pathologically confirmed patients suffering from breast cystosarcoma phyllodes. Results: Breast cystosarcoma phyllodes occurs mainly in the population inbetween 10-year-old and 40-year-old and it has been characterized as the onset of painless breast mass. Not even one definite diagnosis could be made for all 18 patients until after surgical operation. Among the 18 patients, 13 underwent extended resection, another 3 underwent modified mastectomy, and the remaining 2 accepted simple mastectomy. The overall prognosis is good with local recurrence rate at 11.1% (2/18). Conclusion: Auxiliary examination is not of much help towards the conclusive diagnosis of breast cystosarcoma phyllodes, which has to rely on pathological examination. Extended resection is the major method for the treatment of breast cystosarcoma phyllodes and secondary operation can be still effective against local recurrence.   Key words Breast cystosarcoma phyllodes; Diagnosis; Treatment   乳腺叶状囊肉瘤是一种双相分化的肿瘤,由良性的上皮成分和间叶成分组成,是一种少见的纤维上皮性肿瘤,占乳腺肿瘤的0.3%~0.9%,占乳腺纤维上皮性肿瘤的2.5%[1]。1995-2006年我科共手术治疗乳腺肿瘤1 254例,经病理证实乳腺叶状囊肉瘤18例,占1.4%(18/1 254)。现就诊断和治疗探讨如下。   1 资料与方法   1.1 临床资料 本组18例,全为女性,年龄12~44岁,平均21.6岁,其中未婚女性占61.1%(11/18),已婚女性占38.9%(7/18)。病程3月~10年,平均23月。均以无痛性乳房肿块就诊,13例(72.2%)肿块短期内迅速增大,其中61.5%(8/13)分别与月经初潮、妊娠、哺乳有关。肿块全为单发,位于外上象限9例(50.0%),内上象限3例(16.7%),外下象限2例(11.1%),乳腺中央2例(11.1%),全乳2例(11.1%)。肿块最大直径3~15cm,平均6.5cm。肿块均未发现与皮肤和胸肌粘连,未发生破溃,出现局部皮肤血管怒张3例(16.7%),同侧腋淋巴结肿大2例(11.1%)。   术前细针穿刺细胞学检查10例次,均未发

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