第十七章 胺、重氮和偶氮化合物.pptVIP

Hofmann Rearrangement and Curtius Reaction 缺电子， 空轨道 N 在Hofmann 重排反应中，如果发生迁移的烃基碳原子为手性碳，迁移时其构型保持。 Curtius Reaction 酰基氮烯 (i) Alkylation of the sulfonamide derivative of a 1o-amine. Gives 2o-amines.?(ii) Reduction of alkyl imines and dialkyl iminium salts. Gives 2o 3o-amines.? (iii) Reduction of amide derivatives of 1o 2o-amines. Gives 2o 3o-amines 合成2级和3级 胺 Reductive Amination 完成下列转变 The Leuckart Reaction A useful variant of the reductive amination method uses formic acid or formate salts as reductants. Mannich Reaction 11.6 胺的反应（Reactions of Amines）