CUL4B蛤调控cMet通路在肾细胞癌发生发展及靶向药物耐药中的作用及机制研究.docx

优秀毕业论文 精品参考文献资料 山东大学博十学位论文CONTENTS 山东大学博十学位论文 CONTENTS Abstract in Chinese ．．1 Abstract in English 8 Abbreviations 16 Imroduction 1 8 Part I The expression level and role of CUL4B in RCC ．20 Objective ：!() Materials and Methods 20 Results ．38 Part II Influences of CUL4B Regulating c-Met Signaling Pathway in Renal Cell Carcinoma ．．z16 Objective 46 Materials and Methods 46 Results ．5 1 Discussion ．．64 Conclusions 69 References ．．70 Review：the role and mechanism of CRL4 E3 ligases in cancer．．．．．．．．．．．．．．．．．．．．．．．．．．．．．．．．．．．．．．．．．．．．．82 Acknowledgement ．98 List ofpublications ．100 English man