戈之铮大肠癌筛查.pptVIP

溃疡性结肠炎的诊断 2009年7月至2010年6月 19例UC结肠胶囊内镜与传统结肠镜比较 男性12例，女性7例 平均年龄44.16±14.64岁（20-65岁） 戈之铮等.中华消化内镜杂志 2011;28:196-199 轻度 黏膜下血管纹理消失 黏膜细颗粒状改变 黏膜表面发红、小黄色点 中度 黏膜增粗、糜烂、小溃疡 黏膜表面附着脓性分泌物 重度 广泛溃疡 明显的自发性出血 戈之铮等.中华消化内镜杂志 2011;28:196-199 传统结肠镜 胶囊结肠镜 轻度 中度 重度 轻度 2 1 0 中度 0 7 1 重度 0 0 8 传统结肠镜和胶囊结肠镜检查对活动期UC的分级评判 Kappa value=0.826 p-value0.001 戈之铮等.中华消化内镜杂志 2011;28:196-199 * 结肠清洁评判 肠道准备差 肠道清洁良好 戈之铮等.中华消化内镜杂志 2011;28:196-199 各肠段清洁度 戈之铮等.中华消化内镜杂志 2011;28:196-199 戈之铮等.中华消化内镜杂志 2011;28:196-199 胶囊抵达回盲瓣 2.5±1.7h 全结肠转运时间 2.2±2.1h 全消化道转运时间 4.7±2.4h 排出最短时间 2h 排出最长时间 9.8h 转运时间参数 戈之铮等.中华消化内镜杂志 2011;28:196-199 胶囊结肠镜检查指征 不愿或无法进行传统结肠镜检查者 未完成全结肠检查者 对结肠镜检查禁忌而只能进行CT、MRI检查的患者 结肠癌的筛查 * * * * * * * * * * * * * * * * * * * This table summarizes our results There were 18 patients with polyps equal to or larger than 6 mm at colonoscopy Of these 18 patients 8 had polyps equal to or larger than 10 mm at colonoscopy Pillcam colon 2 capsule diagnosed 89% of patients with polyps equal to or larger than 6 mm Pillcam colon 2 capsule diagnosed 88% of patients with polyps equal to or larger than 10 mm Please notice that the confidence interval is rather large due to the relatively small number of patients with polyps Capulse positive but colonoscopy negative studies are defined as false positive studies, therefore specificity pillcam colon 2 was 76% for polyps equal to or larger than 6 mm and was 89% for polyps equal to or larger than 10 mm. * * And this is the reason I make this statement. Our pillcam colon 2 study was very similar to the three pillcam colon 1 studies, out of israel, belgium and europe. Adequate bowel cleansing was similar in all four studies Our study differed just in one aspect, namely the improved technical features added to pillcam colon 2. All three pillcam colon 1 studies revealed a sensitivity ranging from 58% to 64%. The additional 25% of diagnostic sensitivity is to be credited to improved technology. * 结肠胶囊内镜应用前景 上海交通大学医学院附属仁济医院 上海市消化疾病研究所 戈之铮 大肠癌是全球第三最常見癌症 Sung et a