芳胺化反应综述-公开课件（讲义）.pptVIP

芳胺化反应 报告人：张 俊 祥 Scheme 二芳胺化合物 Ullmann condensation of diarylamines with iodobenzenes has been investigated under homogeneous and heterogeneous catalytic conditions with cuprous and curpic salts, as well as powdered copper metal. Copper catalyzed condensation of diarylamines with iodoaromatics is relatively insensitive to substituent (for substituted iodobenzenes p = -0.25; for substituted diphenylamines p = 1.09) but quite sensitive to halogen ( k I / k B , 200). This hypothesis rationalizes many of the perplexing results which typify the literature associated with copper catalyzed nucleo