临床试验的数据管理和统计分析课件.ppt

* * * 1 variabilities depend on subject, study conduct, etc. to say that the “true E” is close to E, we give a range and, since we also are not completely certain of the range, we give it with a statement of probability the reduction is statistically significant. ? The lower limit of 95% CI for E – C is greater than 0. * 1 * 1 * 1 * 1 * 1 Again, a probability statement is needed Absence of evidence should not be confused with evidence of absence. * 1 Also give supportive evidence to its efficacy comparison with placebo * 1 * 1 * 1 三、有效性评价(定量指标) 对基线和不同访视点及其相对基线的评价指标变化进行统计描述，计算例数、均数、