医学免疫学课件10-B细胞及B细胞介导的免疫应答.pptVIP

* * * * * * * * * 主要针对细胞外病原体 * TD-Ag和TI-Ag * * * * * * * * * * * * * * * * * * * * * The interactions of Th cells and B cells in lymphoid tissues The anatomy of humoral immune responses Downloaded from: StudentConsult (on 1 June 2006 03:50 PM) ? 2005 Elsevier Mechanisms of Th cell-mediated activation of B cells B cell-mediated immune response The edge of lymphoid follicle Fully activation Th cells → CD40L cytokines Formation of germinal center Affinity maturation point mutations in the V regions Heavy chain class switching different Ab heavy chain