《BA-0310甜茶复合物抗过敏作用的实验研究》-毕业论文（设计）.docVIP

PAGE PAGE 1 学校代码：10600学 号：0709018 学校代码：10600 学 号：0709018 广西中医学院 学 士 学 位 论 文 BA-0310甜茶复合物抗过敏作用的实验研究 姓 名： 黄琳 院 (系)： 药学院 年 级： 2007 专 业： 中药学 实习单位： 广西壮族自治区妇幼保健院 导师姓名： 李爱媛 完成日期： 2010年 7 BA-0310甜茶复合物抗过敏作用的实验研究 专 业：中药学 申 请 人：黄琳 指导老师：李爱媛 论文答辩委员会 主席： 委员： 目 录 中文摘要········································································3 英文摘要········································································4 1引言············································································5 2实验材料·····································································5 2.1实验材料··································································5 2.2 仪器·········································································5 3方法············································································5 4实验结果·····································································7 5讨 论·········································································10 6结论···········································································11 参考文献······································································11 致 谢·······································································13 中 文 摘 要 目的 本文旨在研究甜茶复合物的抗过敏作用。 方法 1.采用小鼠耳廓肿胀法，观察BA-0310甜茶复合物对2、4-二硝基氯苯(DNCB)所致小鼠DTH(迟发性过敏反应)的影响。2.采用磷酸组胺致敏法观察BA-0310甜茶复合物对磷酸组胺所致豚鼠瘙痒的影响。3.采用氯化乙酰胆碱（Ach）与磷酸组胺引喘法，BA-0310观察甜茶复合物对Ach与磷酸组胺所致豚鼠哮喘的影响。 结果 1. BA-0310甜茶复合物对DNCB所致小鼠迟发性过敏反应有明显的抑制作用，明显抑制小鼠耳廓肿胀。2. BA-0310甜茶复合物对磷酸组胺所致豚鼠瘙痒有明显的抑制作用，提高致痒阈。3. BA-0310甜茶复合物对Ach与磷酸组胺所致豚鼠哮喘有明显的抑制作用，明显延长哮喘潜伏期以及跌倒时间。 结论 BA-0310甜茶复合物具有抗过敏作用。 关键词 BA-0310甜茶复合物，抗过敏，小鼠，豚鼠 The Antiallergic Effects of Rubus suavissimus S. Lee Compexes Experimental Study ABSTRACT [Objective] Objiective to study the antiallergic effects of Rubus suavissimus S. Lee compexes [Methods] stinction used the teste by xylene-induced mouse ear swelling, the pruritus(瘙痒) of skin caused by histamine phosphate, produce wheezing by histamine phosphate and Ach. O