Merck(Online-Blending)默克(在线混料)课件.pptVIP

Active vs. blank formulation: lubrication Lubrication of active vs. blank formulation Pilot scale 活性 vs. 无效配方: 润滑 活性 vs. 无效配方的润滑 试验尺寸 Process scale-up Pilot vs. full-scale Same formulation 过程混料机尺寸增大 试验 vs. 全尺寸 相同配方 Process scale-up - lubrication Pilot vs. full scale Lubrication of blank formulation 过程混料机尺寸增大- 润滑 试验vs. 全尺寸 无效配方润滑 Blend dynamics – large fill volume Lubrication of granule formulation ~ 95% fill volume Lubricant added through bottom of blender 混料动力– 大的填料体积 颗粒配方的润滑 ~ 95% 填料体积 通过混料机底端添加润滑剂 Summary Conclusions A rapid, non-invasive, information-rich approach to blend uniform