微生物法合成红景天苷.pdfVIP

1184 生 物 工 程 学 报 薛飞燕 等/微生物法合成红景天苷 Chinese Journal of Biotechnology /cjbcn Jul. 25, 2019, 35(7): 1184−1192 DOI: 10.13345/j.cjb.180449 ©2019 Chin J Biotech, All rights reserved ·综 述· 微生物法合成红景天苷 薛飞燕，杨明峰，马兰青 北京农学院 生物与资源环境学院 农业部华北都市农业重点实验室，北京 102206 薛飞燕, 杨明峰, 马兰青. 微生物法合成红景天苷. 生物工程学报, 2019, 35(7): 1184–1192. Xue FY, Yang MF, Ma LQ. Microbial synthesis of salidroside. Chin J Biotech, 2019, 35(7): 1184–1192. 摘 要: 红景天苷是红景天属植物的主要有效成分之一，具有耐缺氧、抗辐射、抗疲劳、抗肿瘤、降血糖、提高 免疫力等多重功效。随着其需求量的日益增加和植物资源的不断减少，微生物法合成红景天苷因具有周期短和易 调控等优势而倍受关注。目前微生物法合成红景天苷尚处于基础研发阶段，为了方便相关领域研究者系统了解其 研究现状和探讨其未来发展方向，文中对红景天苷生物合成途径、糖基转移酶、野生菌/ 天然酶资源和工程菌/ 重 组酶体系进行了综述。 关键词: 红景天苷，生物合成途径，野生菌/ 天然酶，工程菌/ 重组酶 Microbial synthesis of salidroside Feiyan Xue, Mingfeng Yang, and Lanqing Ma Key Laboratory of Urban Agriculture (North China), Ministry of Agriculture , College of Bioscience and Resource Environment, Beijing University of Agriculture, Beijing 102206, China Abstract: Salidroside, as one of the main active ingredients of Rhodiala plant, has the effects of anti-hypoxia, anti-radiation, anti-fatigue, anti-tumor, hypoglycemia and improving immunity. With the increasing demand for salidroside and the decreasing of plant resources, microbial production of salidroside has attracted much attention due to its advantages of short period and easy controlling. At present, microbial production of salidroside is still at the basic research stage. In order to make it easier for researchers to understand the advances of microbial synthes