生物化学IILecturenitrogenmetabolism教学讲义.pptVIP

University of Manitoba Adam Burgener Nitrogen metabolism Nitrification and nitrate reduction Nitrogen fixation Nitrogenase NH3 assimilation into organic form Role of glutamate, α-KG, carbamoyl-P Amino acid synthesis Ser, gly Ala, val Asp, Thr Molecules derived from amino acids: creatine Nucleotide biosynthesis Purine, de novo Pyrimidine, de novo Salvage pathways Deoxy nucleotides Nitrogen metabolism, biosynthesis of amino acids and nucleotides Nitrogen has many oxidation states which makes it a very versatile compound From +5 to -3 (nitrate to ammonia) Nitrification and Nitrate reduction Exc