Foley尿管、缩宫素及米索前列醇用于足月妊娠促宫颈成熟的.docVIP

Foley尿管、缩宫素及米索前列醇用于足月妊娠促宫颈成熟的效果比较 谢春艳，唐微，杜子健，章芸 东莞市桥头医院妇产科 广东 东莞523520 基金项目：东莞市社会科技发展（一般）项目（2018507150361485） 摘要 目的 对比Foley尿管、缩宫素及米索前列醇用于足月妊娠促宫颈成熟的效果，以为临床上促宫颈成熟措施的选择提供依据。方法 选择2018年1月到2018年10月期间我院住院待产者120例为研究对象，根据随机数字表法将患者随机分为A组、B组、C组，每组40例，A组釆用Foley尿管小水囊、B组采用米索前列醇、C组采用缩宫素促促宫颈成熟治疗，比较三组临床效果以及阴道分娩者的24h分娩率、引产至临产和分娩时间、总产程、产后出血量，以及新生儿出生Apgar评分、体质量，产褥感染等情况。结果 A组、B组促宫颈成熟有效率（86.00%和90.00%）、阴道分娩率（76.00%和80.00%）比较，差异无统计学意义（P＞0.05），但是A组、B组明显高于C组（50.00%和42.00%），差异有统计学意义（P＜0.05）；B组引产24h内分娩率、引产至临产时间、引产至分娩时间明显短于A组，A组短于C组，差异有统计学意义（P＜0.05）；三组总产程及产后出血量比较，差异无统计学意义（P＞0.05）；三组产妇均未发生产褥感染；三组新生儿体质量、新生儿 Apgar评分比较，差异无统计学意义（P＞0.05）。结论 Foley尿管、米索前列醇用于足月妊娠促宫颈成熟均可取得满意的效果，其中米索前列醇起效更加快速，可以有效缩短产程。 关键词 Foley尿管；缩宫素；米索前列醇；足月妊娠；宫颈成熟 Comparison of Foley catheter, oxytocin and misoprostol for cervical ripening in term pregnancy Xie Chunyan, Tang Wei, Du Zijian, Zhang Yun Department of Obstetrics and Gynecology, Qiaotou hospital, Dongguan Guangdong Dongguan 523520 Abstract Objective To compare the effects of Foley catheter, oxytocin and misoprostol in promoting cervical ripening in full-term pregnancy, so as to provide evidence for the selection of clinical measures to promote cervical ripening. Methods From January 2018 to October 2018, 120 cases of patients in our hospital were randomly divided into group A, group B and group C. Each group had 40 cases. Group A was treated with Foley urethral water sac, group B was treated with misoprostol and group C was treated with oxytocin to promote cervical maturation. The clinical effects were compared in the three groups, and the 24-hour delivery rate of vaginal delivery, the time from induced labor to labor and delivery, total labor process, postpartum hemorrhage, Apgar score, body weight, puerperal infection and so on. Results There was of no significant difference between group A and group B in cervical ripening (86.00% and 90.00%) and vaginal delivery rate (76.00% and 80.00%). But group A and group B were significantly higher than group C (50.00% and 42.00%