respiratoryfailuresj沈静130624C.ppt[兼容模式].PDFVIP

Respiratory Failure 呼吸衰竭 沈 静 Department of Pathophysiology, Zhejiang University School of Medicine The Processes of Respiration Gas Alveolar Tissue Air Alveoli capillary transport cells 气体运输 Ventilation Gas exchange Internal respiration 内呼吸 External respiration 外呼吸 2 1 3 2 4 3 1 Concept Classification 2 Causes Mechanism 3 Functional Metabolic changes 4 COPD 5 ARDS 4 1 Concept Classification 2 Causes Mechanism 3 Functional Metabolic changes 4 COPD 5 ARDS 5 Concept Classification 1. Respiratory Failure 呼吸衰竭 在海平面静息状态吸入空气的情况下，由于肺通气和（或）换 气功能的严重障碍，以致PaO 低于60mmHg （8.0kPa ），伴有或 2 不伴有PaCO2 高于50mmHg （6.67kPa ）的病理过程。 Respiratory failure is a syndrome in which the respiratory system fails in one or both of its gas exchange functions: oxygenation and carbon dioxide elimination. In practice, respiratory failure is defined as a PaO2 value of less than 60 mm Hg while breathing air or a PaCO2 of more than 50 mm Hg.