脑电图机放大电路的设计与仿真.docVIP

　　第25卷　第8期计　算　机　仿　真2008年8月　　文章编号:1006-9348(200808-0300-04 脑电图机放大电路的设计与仿真 刘国立,王一丁 (中国科学院研究生院,北京100049 摘要:在现有生物电放大器研究的基础上,改进并设计了一种符合脑电信号特征的新型高性能放大电路,避免了传统生物电 放大电路冗繁的模拟滤波环节。设计中利用TI公司的低功耗仪表放大器I N A326,得到了较高的共模抑制比;进而通过 50Hz陷波器和低通滤波器,有效地消除了脑电信号强大背景噪声的干扰,实现了微弱脑电信号的放大和采集;最后利用TI2 NA仿真软件对该前置放大电路和50Hz陷波器进行了设计的仿真验证。结果表明,放大电路具有高输入阻抗、高共模抑制 比、低噪声、非线性度小、抗干扰能力强的特点,具有较强的实用性。 关键词:脑电;仿真;共模抑制比;前置放大器;陷波器 中图分类号:TP39119　　文献标识码:B D esi gn and S i m ul a ti on of Am pli f i er of Electroencepha lograph L IU Guo-li,WANG Yi-ding (Graduate University of Chinese Acade my of Sciences,Beijing100049,P.R China ABSTRACT:On the basis of existing bi ol ogical electricity a mp lifier which is studied,a design of ne w type and high perfor mance amp lifier circuit was p r oposed which is in agree ment with the characteristic of the EEG signal and the circuit has p revented the traditi onal design fr om enlarging the m iscellaneous si m ulati on of the circuit and straining the wave link.First,the high Common Mode Rejecti on Rati o(C MRRwas achieved by the use of instru mentati on a m2 p lifier I N A326with l ow consu med power;Then,in order t o eli m inate the str ong backgr ound noises of EEG signal, 50Hz notch filter and l ow-pass filter have been intr oduced in this design and realized the a mp lificati on and collec2 ti on of weak EEG signal.Finally,the feasibility of the design is p r oved according t o the si m ulati on of p reamp lifier and50Hz notch filter by the use of TI N A s oft w are.The results indicate that the circuit has a bright app licable future because of its characteristics of high input i m pedance,high C MRR,l ow noises,l ow degree of nonlinear and high anti -interference ability. KE YWO R D S:Electr oencephal ogra m(EEG;Si m ulati on;Common Mode Rejecti on Rati o(C MRR;p rea mp lifier; Notch filter 1　引言 人体大脑皮层的神经元具有自发的生物电活动,使得大脑皮层经常具有持续的节律性电位的改变,临床上利用双极或单极记录方法在头皮上观察大脑皮层的电位变化,记录到的脑电波称为脑电图(EEG[1]。脑电图机就是用来研究大脑神经细胞活动的精密电子仪器,它能迅速而准确地记录大脑两半球电活动的曲线。 由于脑电信号属于低频微弱的自然信号,其幅值一般在015~100μV,频率为0