细胞增殖、分化及异常.docVIP

Abnormal cell proliferation, differentiation and diseases (细胞增殖、分化异常与疾病 Dept. of Pathophysiology, Zhejiang University School of Medicine (II Regulation of Cell Cycle (细胞周期的调控 Self-control （自身调控）\Cyclin （周期蛋白）和Cyclin dependent kinase（周期素依赖性蛋白激酶, CDK ）\check point（检查点） Extracellular signals（细胞外信号） CDK 活性的调控 (1 Cyclinbinding (2 Phosphorylation and dephosphorylation (3 CDK 抑制因子（cyclin dependent kinaseinhibitor, CDI /CKI） \INK4 (inhibitors of kinase4 family specific for CDK4 and CDK6 p16INK4A , p15INK4B , p18INK4C , and p19INK4D \CIP (Cdkinhibitory protein /KIP (kinaseinhibitory protein famil