英文版实验报告.docVIP

Preparation of Aspirin Purpose of experiment Understand principles and methods of preparation of aspirin Laboratory supplies Acetic anhydride Salicylic acid Strong phosphoric acid Cold water Ice water Distilled water Graduated cylinder Dryer Distillation flasks Alcohol lamp Tripod Asbestos nets Thermometer Rubber plugs Condenser tube Rubber hose Horn tube Erlenmeyer flask Glue applicator Beaker Filter paper Buchner funnel Smoke filter Vacuum pump filter Glass rods Pallet scales Experimental principle and steps Step one : Take 20ml acetic anhydride in the dry distillation of the distillation flask. Take the steam out of 138 ° c above the fractions of 6ml and the rest of the collection.As Figure : Phenomena: 136 ° c began to slip out of the liquid, to 138 ° c will be able to collect the required fraction. Discussion.: New distilled acetic anhydride, as long the acetic anhydride may contain acetic acid, will affect the response. The distillation is not using oil-bath heating, oil-bath heating is designed to control temperature, distillation of acetic anhydride is direct to let its temperature rises. Step two : Take 4 grams of salicylic acid in the Erlenmeyer flask placed in a dry, 6ml new distilled acetic anhydride, and then add 10 drops of concentrated phosphoric acid drops, control heating at 75 ° c water bath for 20 minutes.After this heat, pour the hot water 5ml, full shock, then poured into the 60ml cold water, in the ice water to cool for 15 minutes and see. Phenomena: Water-bath heating finishes, powder reaction of salicylic acid out, only to see the clarification of liquids.Cool in ice water, you can see the solution becomes a white cloudy, with significant crystallization. Chemical equation: Discussion: Concentrated phosphoric acid as a catalyst.Water-bath heating after the hot water 5ml is designed to remove excess acetic anhydride.Because the material is 0.0