cushing_s syndrome a practical approach to diagnosis and differential diagnoses.[2017][journal of clinical pathology][10.cushing_s综合症诊断和鉴别诊断的实用方法。[2017英文精品课件.pdfVIP

Downloaded from / on January 25, 2017 - Published by JCP Online First, published on January 9, 2017 as 10.1136/jclinpath-2016-203933 Best practice Cushing’s syndrome: a practical approach to diagnosis and differential diagnoses Joseph M Pappachan,1 Christian Hariman,1 Mahamood Edavalath,2 Julian Waldron,3 Fahmy W Hanna4 1Department of Endocrinology ABSTRACT early diagnostic work-up and management are Diabetes, New Cross Diagnosis of Cushing’s syndrome (CS) and identification necessary to avoid potential adverse outcomes. This Hospital, The Royal Wolverhampton Hospitals NHS of the aetiology of hypercortisolism can be challenging. best practice article compiles an evidence-based Trust, Wolverhampton, UK The Endocrine Society clinical practice guidelines practical approach to empower clinicians and 2Department of Endocrinology recommends one of the four tests for initial screening of laboratory personnel for diagnostic evaluation of Diabetes, Imperial College CS, namely, urinary-free cortisol, late night salivary CS with the most up-to-date scientific literature. London Diabetes Centre, Abu cortisol, overnight dexamethasone suppression test or a Dhabi, UAE 3Department of Clinical longer low-dose dexamethasone suppression test, for CLINICAL SUSPICION OF CS Biochemistry, University 48 hours. Confirmation and localisation of CS requires Patients with classical signs ma