Ti (II) Mediated Reactions in Organic Chemistry：Ti（II）介导的反应在有机化学.pptVIP

Ti (II) Mediated Reactions in Organic Chemistry Chris Tarr University of North Carolina February 23, 2007 Outline of Topics Covered Background Cyclopropanation Reactions Olefin/Acetylene Functionalizations Reductive Couplings Advantages of Titanium Titanium (IV) reagents are cheap and readily available Low toxicity compared to other transition metal catalysts Less reactive than Li or Mg organometallics More reactive than corresponding B or Zn organometallics Notable Applications Not Covered Sharpless Asymmetric Epoxidation (TiIV)  Lewis Acid Catalysis (TiIV)  McMurry Coupling