EGFR靶向治疗癌症.pptVIP

Current status of EGFR-targeted cancer therapy;S, Surgery; RT, Radiotherapy;CT, Chemotherapy/hormone therapyEGFR, epidermal growth factor receptor;The concept Targeted therapy for a broad range of common solid tumors (including lung, breast, prostate, colon, ovarian, and gastric) Clinical trials Proof of concept well-tolerated therapy tumor responses in several tumor types The potential Improved outcomes in the treatment of common solid tumors;Clinical development of anticancer agents;Clinical development of EGFR-targeted therapies;Cetuximab: approved for the treatment of advanced colorectal cancer;Gefitinib (250 mg/day): approved for the treatment of advanced NSCLC;Erlotinib: awaiting approval for the treatment of advanced NSCLC;Other EGFR-targeted therapies under clinical development;Summary of current EGFR-targeted treatment options