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Application of Genome-wide
Resequencing In Breeding Populations
赵山岑
zhaoshancen@genomics.org.cn
• Dobzhansky:
Nothing in Biology Makes Sense Except in the
Light of Evolution.
• Really?
Nothing in Biology Makes Sense Except in the
Light of Health and Breeding.
2
Understand Breeding
• The nature of domestication events
• Quantitative genetic variation
• Population genomics-based approaches
3
Part I
• The nature of domestication events
– The Domestication Syndrome
– The Domestication Process
– Genes Controlling Domestication Traits
What is domestication
• Domestication is a complex evolutionary process in which
human use of plant and animal species leads to
morphological and physiological changes that distinguish
domesticated taxa from their wild ancestors.
• For example
Maize, Rice, Wheat, Tomato, and so forth.
• Darwin’s evidence
• Homo special?
Some fungal species have been domesticated by ants
and beetles.
• Plant-animal co-evolution
The Domestication Syndrome
• larger fruits or grains, more robust plants
• more determinate growth or increased apical dominance
• loss of natural seed dispersal so that seeds remain attached to
the plant for easy harvest
• crops often have fewer (although larger) fruits or grains.
• A variety of physiological changes are also involved. These
include a loss of seed dormancy, a decrease in bitter
substances in edible structures, changes in photoperiod
sensitivity, and synchronized flowering.
Convergent and parallel evolution
• Convergent phenotypic evolution
– the appearance of the same trait in independent
evolutionary
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