NCCN胃癌指引解读.pptVIP

GAST-3:T3,T4 or any T,N1 after R0 resection 2008.v.1NCCN guideline ： RT,45-50.4Gy+concurrent 5-FU based radiosensitization(preferred)+5-FU ± leucovorin or ECF if received preoperatively （ category 1 ） Recommendation of Chinese version: Add foot note ? If D0/D1 resection: agreed the above; ? If D2 resection: postoperative chemotherapy recommended. Evidence ： ? D0/D1 operation consists more than 90% in INT0116 ； ? 2 Meta analysis about adjuvant chemotherapy ? GASC-study Patients: 23 trials ， 4919 pts Methods: Adjuvant chemotherapy arm(Arm A): 2441 Observati