2008年中国生物技术产业发展报告.docVIP

2008年中国生物技术产业发展报告 组织工程与再生医学 2008’ Development Report on Biotechnology Industry of Tissue Engineering Regenerative Medicine in China 曹谊林 YiLin Cao 组织工程国家工程研究中心 National Abstract The loss or dysfunction of tissues and organs is one of the main threats for concern in human health care and also the most important cause of diseases and even death. By traditional treatment methods, it’s hard to solve many fundamental problems such as defect or failure of tissues and organs. Currently, exploring the ways to radically solve these most challenging medical problems has become the urgent frontier focus in the global science, especially in the life science. Regenerative medicine is a new science field that applies the principles and methods of modern life science, materials science, computer science, engineering and other fields to develop some new ways to amplify the natural healing process in the places it is needed most, or take over the function of a permanently damaged organ. As the core of regenerative medicine, tissue engineering, based on the major leading achievements of cell biology and engineering science, is an emerging way of rebuilding substitutes in vivo or in vitro by combinations of bioactive cells with biological materials, promising a new way of maintaining, restoring, renewing or improving the function of damaged tissues and organs. The central task of tissue engineering is to construct the three-dimensional cell-scaffold complexes, which provide the important circumstances for cells to adapt their state for the synthesis of extracellular matrix proteins, neogenesis and functioning of tissue structures. It is on the level of tissue that tissue engineering is performed. With the establishment and development of such conception and approach used in tissue engineering, it has been regarded as a revolution in the field of surgery and pushed us forward from the procedures of tissue repair and replacement by synthetic structures, which have dominated this area