病理学英文课件：传染病.pptVIP

* Pathological changes of secondary syphilis Generalized lymphadenopathy: nonspecific follicular hyperplasia Mucocutaneous lesions ：maculopapular, scaly or pustular Microscopy: Proliferative endarteritis Inflammatory infiltrate rich in plasma cells Spirochetes readily demonstrable，serologic test positive Resolve several wks * Cardiovascular syphilis: syphilitic aortitis梅毒性主动脉炎 ~80% endarteritis of the vasa vasorum（滋养血管） of the proximal aorta → scaring of the aortic media→ progressive dilation of the aortic root and arch→aortic insufficiency and aneurysms of the proximal aor