生理学教学课件：Physiology of the Blood Vessels.pptVIP

影响静脉回流的因素 影 响 因 素 静脉回流量 体循环平均压↑ ↑ 心缩力（心泵）↑ ↑ 骨骼肌收缩（肌泵）↑ ↑ 呼吸运动（呼吸泵）↑ ↑ 体位：卧→立 ↓ （头部回流↑下肢回流↓） 立→卧 ↑ （头部回流↓下肢回流↑） V.Formation and Factors effecting of Interstitial Fluid The Interstitial Fluid Water within the body accounts for 60% of the total body weight (body fluid) 2/3 intracellular compartment 1/3 extracellular compartment (80%, interstitial fluid; 20%, blood plasma) The distribution of extracellular fluid between the plasma and interstitial compartments is in a state of dynamic equilibrium. Tissue fluid is not normally a “stagnant pond” but is rather a continuously circulating medium, formed from and returning to the vascular system. In this way, the tissue cells receive a continuously fresh supply of glucose and other plasma solutes that are filtered through tiny endothelial channels in the capillary walls Formation and Factors effecting of Interstitial Fluid 1. Formation and Circumfluence Effective filtration pressure ①+capillary blood pressure +30mmHg ②+colloid osmotic pressure of interstitial fluid +15mmHg ③-plasma colloid osmotic pressure -25mmHg ④-interstitial hydrostatic pressure -10mmHg π= C R T（菲茀尔定律） π：以大气压为单位的渗透压 C ：某溶液克分子浓度 R：气体常数=0.082 T：绝对温度=2730C Formation of Interstitial Fluid Pc : pressure in the capillary Pif : hydrostatic pressure of interstitial fluid πP : colloid osmotic pressure of the blood plasma πif : colloid osmotic pressure of the interstitial fluid Effective filtration pressure = （毛细血管血压+组织液胶体渗透压) – （血浆胶体渗透压+组织液静水压） 促进滤过力量 阻止滤过力量 capillary A = ( 30mmHg + 15mmHg ) – ( 25mmHg + 10mmHg ) = 10mmHg capillary V= (12mmHg + 15mmHg) – (25mmHg + 10mmHg) = - 8mmHg colloid osmotic pressur