超滤系统的基本组成和操作.pdfVIP

Basic Components Operation of TFF Systems 超滤系统的基本组成和操作 TFF Overview 超滤回顾 • Components Controls组成控制 • Equations and Definitions公式和定义 • Step by Step Operation of the process 过程操作的步骤 Basic TFF System Hardware 基本超滤系统的硬件 • Minimum Requirements:最基本的配置要 : – Pumps泵 – Holder, Filter module, Piping and Tubing 夹具,过滤膜,管路管件 – Tank with Mixerd带搅拌的罐 – Retentate Valve(usually a sanitary diaphragm valve)回流阀(通常 是卫生级的隔膜阀) • Important Additions for proper operation:正确操作的重要条件 – Pressure Gauges/Indicators - feed, retentate, permeate压力表/ 指示器-进口,回流,透出 – Flow Meters - retentate and permeate流量计- 回流和透出 – Extra Valves for cleaning and controlling flow清洗和控制流速的 额外阀门 – Thermometer温度计 – pH, Conductivity, UV Meters PH, 电导率,紫外计 – Heat Exchanger for cooling or heating 用于冷却或加热的热交换器 Calculating a TFF Trial 超滤试验的计算 Collect the right information before you start 在你开始前收集正确的信息 • Basic Parameters 基本参数 (you’re already familiar with)(你已经熟悉) – Operating Pressures Ranges - TMP, and delta P – 操作压范围-TMP,和ΔP – Typical Flux - J (obtained from literature) – 典型流速-J( 由资料获得) • Other important information you will need 其他你需要的重要信息 – Product Recovery: Yield - Y, Passage - P, Rejection –R – 产品回收:回收率-Y,透过率-P,截流率-R – Volumes :Initial - Vo, Final-Vf – 体积:初始-VO,最后-VF – Typical Flow and Recirculation Rates – Q – 典型流量和循环率-Q – Time for the Trial – T – 试验的时间-T – Installed Membrane Area – A – 安装膜的面积 – Concentration Factor – CF 浓缩因子-CF – Buffer Wash Volumes - DF (Diafiltration Volumes) 缓冲溶液冲洗体积-DF(透析体积) TFF Definitio