病理学与病理生理学 病理学与病理生理学 慢性萎缩性胃炎双语介绍.docVIP

慢性萎缩性胃炎 病史：男性，62岁。上腹胀痛30余年，进行性消瘦、贫血10年。因肺炎伴感染性休克死亡。 肉眼形态，病变主要在胃窦部或胃体部，呈灶性或弥漫性分布。病变胃粘膜萎缩变薄，皱襞变平或消失，颜色灰白，粘膜下血管透见。 组织学形态，胃粘膜变薄，固有腺体萎缩、稀疏。部分腺体可见肠上皮化生。固有膜可见淋巴细胞、浆细胞浸润，并有淋巴滤泡形成。 Chronic atrophic gastritis Case abstract: Male, 62 years old. Patient suffered upper abdominal pains for more than 30 years, progressive thinness and anemia for 10 years. Patients died of pneumonia accompanying infective shock. Gross morphology, lesion mainly distributes in gastric antrum and gastric body focally or diffusively.The mucosa of the stomach becomes thinned or flattened and shows grey color, revealing more readily the submucosal vasculature. Rugal folds are flattened or disppear. Histopathology, mucosa glands become lessen, and persisting glands atrophy and disappear. Mucosa may become partially replaced by metaplastic columnar absorptive cells and goblet cells of intestinal morphology.Inflammation of the lamina propria involves lymphocytes and plasma cells.