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WHO Library Cataloguing-in-Publication Data WHO handbook for guideline development. 1.Guidelines as a topic – standards. 2.Review literature. 3.Meta-analysis. 4.Peer review. 5.Evidence-based medicine. 6.World Health Organization. I.World Health Organization. ISBN 978 92 4 154844 1 (NLM classification: WA 39) © World Health Organization 2012 . Publications of the World Health Organization are available on the WHO web site () or can be purchased from WHO Press, World Health Org