贵阳市老年人群维生素D水平及与老年性疾病的相关性研究.docxVIP

贵阳市老年人群维生素D水平及与老年性疾病的相关性研究 Correlation between vitamin D levels and senile diseases in the elderly in Guiyang LIU Taozhen1 WANG Limin2 DENG Yi1 SHI Lan1 ZENG Xiaoqiong1 LI Yamin1 DING Jiaxiu1 1.Department of Geriatrics， Guiyang First Peoples Hospital， Guiyang *****， China; 2.Outpatient Department， Guiyang First Peoples Hospital， Guiyang *****， China [Abstract] Objective To investigate the relationship between vitamin D levels and senile diseases in the elderly in Guiyang. Methods A total of 5913 elderly patients who underwent vitamin D examination in Guiyang First Peoples Hospital from April 2013 to June 2019 were enrolled. The serum 25-hydroxyvitamin D3 test results were divided into vitamin D deficiency， lack and normality. According to the clinical diagnosis， the patients were divided into hypertension group， heart failure group， stroke group， diabetes group and healthy control group. The clinical data were retrospectively analyzed. The relevance of vitamin D level and senile diseases in the elderly in Guiyang was explored. Results The average level of 25-hydroxyvitamin D3 was 20.797 ng/mL， of which there were 3137 cases of 25-hydroxyvitamin D3 deficiency （20 ng/mL）， accounted for 53.03%; 1722 cases of vitamin D3 insufficiency （20 ng/mLD330 ng/mL）， accounted for 29.13%; and 1054 cases of normal vitamin D3 （30 ng/mL）， accounted for 17.84%. The level of vitamin D3 in healthy normal control group was significantly higher than that in hypertension group， heart failure group， stroke group and diabetes group （P0.05）. There were no significant differences in serum 25（OH）D levels between the hypertension group， the heart failure group， the stroke group， and the diabetes group（P0.05）. Serum 25（OH）D levels were statistically different between different severity in the hypertension group， the heart failure group， the stroke group， and the diabetes group （P0.05）. The higher the severity of the disease， the lower the serum 25（OH）D level. There was a negative c