米非司酮与卡孕栓在无痛人流术中的临床应用.docVIP

米非司酮与卡孕栓在无痛人流术中的临床应用 龙梅，李霞，艾海权，张威，李晓兰，腊晓琳 (新議医科大学第一附属医院生殖助孕中心，乌鲁木齐830054) 摘要：！的探讨米非司爾与卡孕栓用于无痛人流术的临床效果。方法将2009年3-12月在新體医科大学第一附属医院计划生 育门诊就诊、自愿要求行无痛人流术的未产及剖宫产术后的早孕妇女1 260例，随机分为3组：米非司酮组(450例)：术前口服米非 司酮2 d，总呈150 mg；卡孕栓组(410例)：术前60 min阴道放置卡孕栓1 mg；对照组(400例)术前不用药。观察3组宫颈软化程 度、术中出血邑手术时间、不良反应的发生情况o结果3组宫颈软化程度、术中出血邑手术时间经比较差异有统计学意义(_P0.05) 米非司酮组与卡孕栓组宫颈软化程度、副反应的发生情况比较差异无统计学意义(P0.05)米非司酮组较卡孕栓组术中出血屋少、手 术时间短，差异有统计学意义(P0.05)。结在无痛人流术中，米非司酮与卡孕栓都能有效软化宫颈，但减少术中出血量和缩短手术 时间优于卡孕栓，増加了无痛人流术的安全性，值得临床推广应用。 关键词：米非司酮；卡孕栓；无痛人流术 中图分类号：R713.9 文献标识码：A 文章编号=1009-5551 (2012)10-1383-04 Clinical use of mifepristone and carboprost methylate suppositoriesinpainless inducedabortion LONG Me 1, LI Xia, Al Hai-quan, ZHANG Wei, LI Xiao-Ian, LA Xiao-lin (Department of Infertility Cent(八匚 The First Affiliated Hosp, , Urumqi 830054, China) Abstract : Objective To study the clinical eefect of mifepristone and carboprost methylate suppositories in painless induced abortion. Methods One thousand and twenty sixty cases of painless induced abortion that haven71 delivery through vaginal and pregnancy after cesarean section were randomly divided into three groups : mifepristone group : (n =450) , before operation oral mifepristone 150 mg in two days ； carboprost methylate suppositories group T =410) , sixty-minter before operation placed carboprost methylate suppositories 1 mg into vaginal ； control group (n =300) : before operation no drug was used? Then observe the degree of cervical dilator , t he amount of bleeding , t he length of operation and the side effect in three groups. Results The difference of the degree of cervical dilator ,the amount of bleeding the length of op-基金项目： 国家?十一五”科技支撐项目子课题(2007BAZ07A14) 作者筲介:龙梅(973 —)，女，硕士.副主任医师.研究方向，生殖医学及优生优育。 jSflf作者:腊晓琳■女.硕士生导师■主任医师t副教授t研究方向：生殖医学及优生优育,E-mail： xiaolinla@o eration were significant in three groups (P 10 ? 05) ； mifepristone group compared with carboprost methylate suppositories group, the degree of cervical dilator and side effect were no statistically signifi