综述国自然标书生物医学37 programming bugs microbiota and the developmental origins of brain health and disease.pdfVIP

Accepted Manuscript Programming Bugs: Microbiota and the Developmental Origins of Brain Health and Disease Martin G. Codagnone, Simon Spichak, Siobhain M. O’Mahony, Olivia F. O’Leary, Gerard Clarke, Catherine Stanton, Timothy G. Dinan, John F. Cryan PII: S0006-3223(18)31605-6 DOI: 10.1016/j.biopsych.2018.06.014 Reference: BPS 13570 To appear in: Biological Psychiatry Received Date: 15 March 2018 Revised Date: 29 May 2018 Accepted Date: 18 June 2018 Please cite this article as: Codagnone M.G., Spichak S., O’Mahony S.M., O’Leary O.F., Clarke G., Stanton C., Dinan T.G. Cryan J.F., Programming Bugs: Microbiota and the Developmental Origins of Brain Health and Disease, Biological Psychiatry (2018), doi: 10.1016/j.biopsych.2018.06.014. This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal per n. ACCEPTED MANUSCRIPT Programming Bugs: Microbiota and the Developmental Origins of Brain Health and Disease Martin G. Codagnone1,2*, Simon Spichak1,2*, Siobhain M. O’Mahony1,2, Olivia F. O’Leary1,2, T Gerard Clarke1,3,4, Catherine Stanton1,4,5, Timothy G. Dinan1,3, John F. Cryan1,2 1APC Microbiome Ireland, University College Cork, Ireland 2Department of Anatomy and Neuroscience, University College Cork, Ireland 3Department of Psychiatry and Neurobeh ioural Science, University College Cork, Cork, S Ireland. 4Irish Cen