病毒的基因组与结构.pptxVIP

Viral Genome and Structures/special/opencourse/virology.htmlBreakthrough in 1950’sThe viral nucleic acid genome carries the information needed to replicate, build, and spread virions in the world.One of the building blocks of Molecular BiologyT4, TMVHershey-Chose experimentwith phage T4Fraenkel-Conrat’s work with TMVSeven Genome TypesEither DNA or RNAStructurally diverse: linear, circular, segmented, gapped, single-stranded (+) strand, single-stranded (-) strand, single stranded (ambisense), double-stranded, some have covalently attached proteins, some have cross-linked ends of double-stranded