心血管风险(一级预防).ppt

* Statin added to CCB-based therapy significantly reduced fatal CHD and nonfatal MI 53% (CI 0.32–0.69, P = 0.001) relative to CCB therapy alone. Statin added to beta-blocker–based therapy demonstrated a nonsignificant 16% reduction in fatal CHD/nonfatal MI (CI 0.60–1.17, P = 0.30) vs beta-blocker therapy alone. ASCOT: Integration of antihypertensive regimens with statin * Statin added to CCB-based therapy significantly reduced CV events and procedures 27% (CI 0.60–0.88, P = 0.001) relative to CCB therapy alone; while statin added to beta-blocker therapy showed a nonsignificant 15% reduction i