儿童过敏性紫癜336例临床分析.docxVIP

儿童过敏性紫瘢336例临床分析 【摘要】 目的：探讨儿童过敏性 紫瘢的临床特点和治疗方案。方法：对2001 年8月?2007年10月在本院住院的336例 过敏性紫瘢患儿的发病特点、临床表现、肾 损害相关因素及预后等方面进行回顾性分 析。结果：2001?2007年每年的住院构成比 依次为％ % % % % 骸% 农村患儿213 例，占％诱因：感染因素216例，进食特 殊食物引起64例，药物引起56例。冬季发 病148例，春季发病130例。出现肾脏症状 64例，出现关节症状74例，出现消化道症 状70例。血清IgA升高58例，IgE升高102 例。预后：治愈276例，好转32例。结论： HSP患病率有逐年升高趋势；农村患儿发病 较多；冬春季好发。发病诱因仍以感染为第 一位。要重视儿童过敏性紫瘢的多系统损害， 如皮肤、关节、消化道、肾脏等。发病与上 呼吸道感染和机体免疫功能紊乱有关。 【关键词】儿童紫瘢过敏性临床特点 Clinical Analysis of 336 Children with Henoch Schonlein Purpura ZHOU Bin, LI Li da (Xuzhou Central Hospital of Jiangsu Province, Jiangsu Xuzhou 221009, China) I Abstract ] Objective:To study the clinical characteristics and treatment of children with Henoch Schonlein purpura (HSP). Methods: 336 cases with HSP hospitalized in our hospital from August, 2001 to October, 2007 were retrospectively studied on their patterns of onset, clinical manifestations, correlated factors of renal damage and outcomes. Results: (1) The constituent ratio of hospitalization of HSPWas %, %, %, %, %, % and % from 2001 to 2007, respectively. ⑵ Among the 336 cases, 213 (%) were from rural area. (3) Inducing factors: infections (216 cases, %), special food (64 cases, %) and drugs (56 cases, %). (4) Winter 148 cases (%), Spring 130 cases (%). (5) Totally 64 cases (%) presented symptoms of renal damage, 74 cases (%) presented symptoms of joint symptoms, 70 cases (%) presented symptoms of gastrointestinal tract symptoms. (6) Increased IgA in serum in 58 cases (%), increased IgE in 102 cases (%). (7) Pprognosis: 276 (%) cases were cured, 32 cases (%) were greatly improved. Conclusions: (1) Morbidity of HSPincreases year by year. Morbidity is high in the children from rural area and also high high whenin winter and spring. (2) The most important inducing factor is infection. (3) Special attention should be paid to niLilli system damage in HSP, including skin, joint, gastrointestinal tract and renal. (4) HSP has relation with upper respiratory tract infection and functional disorder of immune