围术期多模式镇痛新理念.pptVIP

Johns N, ONeill S, Ventham NT, Barron F, Brady RR, Daniel T. Clinical effectiveness of transversus abdominis plane (TAP) block in abdominal surgery: a systematic review and meta-analysis.[J] Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland ;14(10):e635-42 一项纳入9个RCT〔n=413)，以外周神经阻滞+吗啡为实验组，吗啡+抚慰剂为对照组的meta分析发现，实验组和对照组疼痛评分无统计学差异，但实验组术后24h和48h吗啡消耗量显著减低，恶心、呕吐等不良反响减少，差异具有统计学意义； 2021/1/12 * 普瑞巴林〔pregabalin〕 给药途径：PO 作用机制：与α2δ亚基结合抑制Ca2+内流； 副作用：头晕嗜睡、视物模糊、外周水肿等副作用； Both medications〔加巴喷丁和普瑞巴林〕 are associated with reduced opioid req