EAU20上尿路尿路上皮癌指南.pdfVIP

EAU GUIDELINES ON UROTHELIAL CARCINOMA OF THE UPPER URINARY TRACT (UTUCs) 上尿路尿路上⽪癌 （ ）指南 EAU UTUC (Text up date March 2020) （更新于 年 ⽉） 2020 3 M. Rouprêt, M. Babjuk, M. Burger, E. Compérat, N.C. Cowan, P. Gontero, A.H. Mostafid, J. Palou, B.W.G. van Rhijn, S.F. Shariat, R. Sylvester, R. Zigeuner Guidelines Associates: O. Capoun, D. Cohen, J.L. Dominguez-Escrig, B. Peyronnet, T. Seisen, V. Soukup Epidemiology 流⾏病学 Upper urinary tract urothelial carcinomas (UTUCs) are uncommon and account for only 5-10% of urothelial cell carcinomas (UCs). They have a similar morphology to bladder carcinomas and nearly all UTUCs are urothelial in origin. 上尿路尿路上⽪癌 （ ）并不常⻅，仅占尿路上⽪细胞癌 （ ）的 。 和膀 UTUC UC 5-10% UTUC 胱癌的形态学相似，并且⼏乎所有的UTUC 都起源于尿路上⽪。 Recommendations Strength rating 建议 推荐强度 Evaluate patient and family history based on the Amsterdam criteria to Weak identify patients with upper tract urothelial carcinoma. 弱 根据阿姆斯特丹标准评估患者及家族史，以识别上尿路尿路上⽪癌患 者。 Evaluate patient exposure to smoking and aristolochic acid. Weak 评估患者的吸烟情况以及⻢铃兜酸暴露情况。 弱 Staging and grading systems 分期和分级系统 The UICC 2017 TNM (Tumour, Node, Metastasis Classification) for renal pelvis and ureter is used for staging (Table 1). 指南使⽤了 肾盂和输尿管 （肿瘤、淋巴结、转移）分期系统 （表 ）。 2017 UICC TNM 1 Tumour grade 肿瘤分期 The 2004/2016 WHO classification distinguishes between non-invasive tumours: 2004/2016 年WHO 分级标准对⾮浸润性肿瘤进⾏了区分： • papillary urothelial neoplasia of low maligna