间质干细胞及急性肺损伤.pptVIP

内皮渗透性、上皮通透性和肺泡液体间隙 increased protein of the endothelial and epithelial barriers, and reduced (or insufficient) alveolar fluid clearance (AFC). MSCs reduce the increase in endothelial permeability ALI. BAL albumin and protein are commonly used as markers of lung endothelial permeability。 在肺泡水肿形成： 内皮蛋白质通透性的增加； 上皮屏障破坏， 肺泡液体清除率下降。 MSC能够减少ALI内皮通透性。BAL中白蛋白和蛋白质含量通常用作的肺内皮通透性指标。 第三十页，共58页。 BAL albumin, total protein, and immunoglobulin M (IgM) were increased 3 days following intratracheal LPS. This increase was attenuated by MSCs given intravenously 30 minutes after the injury. Angio