丙戊酸钠对青春期女性患者的内分泌影响PPT课件.ppt

* 德巴金和多囊卵巢综合征。 * 普通人群中多囊卵巢的发病率是22%，癫痫妇女的发病率是38% 普通人群中多囊卵巢综合症的发病率是12%，癫痫妇女的发病率是25% Rates of PCO and PCOS in the General Population and Women With Epilepsy. An expert consensus panel convened on June 10, 2002 to review issues pertaining to polycystic ovarian syndrome and women with epilepsy and bipolar disorder. The panel reported that polycystic ovaries are found in as many as 22% of the general premenopausal female population,1 compared with up to 38% of women with epilepsy. They said that PCOS has been reported in up to 12% of the general premenopausal female population and in up to 25% of women with epilepsy.2,3 Members of the Polycystic Ovarian Syndrome Expert Panel: Andrea E. Dunaif, MD, Northwestern University Feinberg School of Medicine, Chicago, Illinois. David A. Ehrmann, MD, the University of Chicago, Chicago, Illinois. Andrew G. Herzog, MD, Beth Israel Deaconess Medical Center, Wellesley, Massachusetts. Richard S. Legro, MD, Hershey Medical Center, Hershey, Pennsylvania. Natalie L. Rasgon, MD, PhD, UCLA School of Medicine, Los Angeles, California. References 1. Genton P, et al. Epilepsia. 2001;42:295-304. 2. Herzog AG, et al. Epilepsia. 2001;42:311-315. 3. Dunaif A, et al. Annu Rev Med. 2001;52:401-419. * 读片 Polycystic Ovarian Syndrome (PCOS) Versus Polycystic Ovaries (PCO). It is important to distinguish between polycystic ovaries (PCO) and polycystic ovarian syndrome (PCOS). PCO is frequently defined by ultrasonographic and anatomic criteria as the presence of multiple ovarian cysts 2 to 8 mm in diameter and increased ovarian stroma and/or size.1 As noted earlier, PCO is not intrinsically pathologic.2 The definition of PCOS differs in the United States and Europe: In the United States, PCOS is defined as a metabolic syndrome, and anatomic changes need not be present for diagnosis. In Europe, PCOS generally is defined as PCO in the presence of 1 or more clinical signs of endocrine dysfunction, such as menstrual irregularity, hirsutism, or infertilit