胃肠道间质瘤CD117CD34和Ki67的表达与临床病理因素的相关性临床医学.docVIP

胃肠道间质瘤CD117CD34和Ki67的表达与临床病理因素的相关性临床医学 目录 TOC \o 1-9 \h \z \u 目录 1 正文 1 文1：胃肠道间质瘤CD117CD34和Ki67的表达与临床病理因素的相关性临床医学 1 1 资料和方法 3 2 结果 4 3 讨论 5 文2：耐药基因TopoⅡ及Ki67在食管鳞癌的表达临床医学 7 1 材料与方法 8 2 结 果 9 3 讨 论 10 参考文摘引言： 11 原创性声明（模板） 13 文章致谢（模板） 13 正文 胃肠道间质瘤CD117CD34和Ki67的表达与临床病理因素的相关性临床医学 文1：胃肠道间质瘤CD117CD34和Ki67的表达与临床病理因素的相关性临床医学 Abstract Objective:To investigate the expression rates and the expression levels of CD117、CD34 and Ki-67 in gastrointestinal stromal tumo (GISTs) and its relatiohip with the clinicopathological features and risk rank of : To detect the expression rates and the expression levels of CD117、CD34 and Ki-67 in 57 cases of GISTs by immunohistochemical S-P,and to analysis the relatio of immunohistochemistry of the above indicato and related clinicopathological facto (gender,age,location).To further explore the relatiohip of the rank of risk and immunohistochemistry of the above : The positive expression rates of CD117 and CD34 were % and %.There had no significant difference in the different gender and age group on the positive expression rates of positive expression rates of CD34 in parenteral is higher than that of positive Expression inteity of CD117 and the proliferation index of Ki-67 is significant different in the different rank of risk(P).The positive expression inteity of CD117 and the proliferation index of Ki-67 was positively correlated with risk : CD117 and CD34 in GIST was in high expression levels,and had a certain significance in the diagnosis of the expression inteity of CD117 and the proliferation index of Ki-67 was positively correlated with risk classification. They may be one of indicato in judging the risk of GIST. Key words Gastrointestinal Stromal Tumor;CD117;CD34;Ki-67;Risk 胃肠道间质瘤(gastrointestinal stromal tumor，GIST)是一类发生于胃肠道的最常见的间叶源性肿瘤，在形态学上主要由梭形细胞和上皮样细胞组成，镜下很难与平滑肌瘤、平滑肌肉瘤和神经鞘瘤相区别。近年来，随着免疫组化的开展和电镜研究的深入，人们对GIST有了新的认识。本研究通过对57例GIST标本进行光镜观察及免疫组化检测，以进一步探讨GIST免疫组化的结果及其与临床病理相关因素和危险度分级的关系。 1 资料和方法 资料 收